By Philipp L. Rautenberg, Andrey Sobolev, Andreas V. M. Herz, Thomas Wachtler (auth.), Abdelkader Hameurlain, Josef Küng, Roland Wagner, Christian Böhm, Johann Eder, Claudia Plant (eds.)
The LNCS magazine Transactions on Large-Scale facts- and Knowledge-Centered Systems specializes in information administration, wisdom discovery, and data processing, that are middle and sizzling subject matters in laptop technology. because the Nineteen Nineties, the web has turn into the most driver in the back of software improvement in all domain names. a rise within the call for for source sharing throughout diverse websites hooked up via networks has ended in an evolution of knowledge- and knowledge-management platforms from centralized structures to decentralized platforms permitting large-scale allotted functions supplying excessive scalability. present decentralized platforms nonetheless specialise in info and data as their major source. Feasibility of those platforms is predicated primarily on P2P (peer-to-peer) ideas and the help of agent structures with scaling and decentralized regulate. Synergy among Grids, P2P platforms, and agent applied sciences is the main to facts- and knowledge-centered structures in large-scale environments.
This precise factor of Transactions on Large-Scale facts- and Knowledge-Centered platforms highlights a number of the significant demanding situations rising from the biomedical functions which are presently inspiring and selling database learn. those comprise the administration, association, and integration of big quantities of heterogeneous information; the semantic hole among high-level examine questions and low-level facts; and privateness and potency. The contributions hide a wide number of organic and scientific purposes, together with genome-wide organization reports, epidemic learn, and neuroscience.
Read or Download Transactions on Large-Scale Data- and Knowledge-Centered Systems IV: Special Issue on Database Systems for Biomedical Applications PDF
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Extra info for Transactions on Large-Scale Data- and Knowledge-Centered Systems IV: Special Issue on Database Systems for Biomedical Applications
Tags here might also be aimed at pointing out possible problems in the interpretation of the intensity proﬁles. Again, the obtained fasta sequence must be precisely related to the studied exact sequence (but this information can be obtained automatically from previous annotations on the samples worked out). 30 A. Bechini and R. Giannini The ﬁnal diagnosis is suitable to be tagged with standard notations for the mutations possibly found in the sample . Although here no ontological information is apparently embedded, the mutation code can be related (out of the context of the used software framework) to other ontological models associated to the mutation.
Leading to the deﬁnition of the CMIS directives ; such eﬀorts are paving the way to the actual federation (at least under the search perspective) of locally developed document bases. Following this approach in the biomedical domain, researchers and clinicians might be given a new extraordinary source of information. Semantic search can be carried out only if the documents in the knowledge base have been properly annotated with unambiguous, standard terms . Standardization eﬀorts in this direction lead to the development of controlled vocabularies as the well-known MeSH  in the biomedical ﬁeld.
Upon such a selection, a graphical representation for the chosen ontology it is shown in the web user interface, and it can be interactively explored for an easy identiﬁcation of interesting concepts. To this aim, we made use of a force-directed graph layout for an animated visualization, where nodes are ontology concepts and links between nodes represent a parent-child relation, as shown in Fig. 8. Interactive navigation is performed by acting upon the nodes that, once clicked, reveal direct children (if present).