By Thomas Schrader, Andrew D. Hamilton
A well timed assessment of this rapidly-expanding subject, masking crucial sessions of compounds and incorporating the most recent literature. With its application-oriented method, this publication is the 1st to stress present and strength functions, extending to such fields as fabrics technological know-how, bioorganic chemistry, medicinal chemistry, and natural synthesis. within the organic context particularly, the e-book clarifies which receptor structures paintings good in water or larger below physiological stipulations. From the contents: * Amino Acid, Peptid and Protein Receptors * Carbohydrate Receptors * Ammonium, Amidinium and Guanidinium Receptors * Anion Receptors * Molecular tablets and Self meeting * Dynamic Combinatorial Libraries in line with Molecular attractiveness * Molecular Machines * Self-Replication aimed toward graduate scholars and experts within the box, this can be additionally of curiosity to pharmaceutical businesses thinking about drug layout, in addition to chemical businesses with a polymer or nanotechnology crew. furthermore, analytical businesses engaged on the complex apparatus coated the following will locate stimulating new purposes.
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Four of these loops generally take up a hairpin conformation and the remaining two form more extended loops. As a mimic, calixarene was used as a rigid cyclic scaffold and the upper rim was functionalized with cyclic peptides containing an artificial 3-aminomethylbenzoyl amino acid to facilitate coupling to the platform (Fig. 12) . 12 Design of an artificial receptor for chymotrypsin surface recognition. face originating from the presence of several lysine and arginine residues. To introduce complementary charge in the antibody mimic the negatively charged sequence GlyAspGlyAsp was used in the loops.
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