By Kathleen M. Kantak, Joseph G. Wettstein
This ebook highlights the behavioral and neurobiological concerns suitable for drug improvement, stories facts for an cutting edge procedure for drug discovery and offers views on a number of distinctive subject matters starting from healing drug use in young children, rising applied sciences and non-pharmacological methods to cognitive enhancement.
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Additional resources for Cognitive Enhancement
There is wide support in the literature demonstrating the applicability of the VPC paradigm to disease state, particularly for Alzheimer’s disease. For example, the VPC test has been demonstrated to distinguish those subjects who are aging normally from those with mild cognitive impairment and Alzheimer’s disease. Most recently, Zola et al. (2013) reported that scores on the VPC paradigm not only reveal present disease state, but are also predictive of disease progression (Zola et al. 2013). L.
J Clin Exp Neuropsychol 31:462–471 Harvey PD, Sabbag S, Prestia D et al (2012) Functional milestones and clinician ratings of everyday functioning in people with schizophrenia: overlap between milestones and specificity of ratings. J Psychiatr Res 46:1546–1552 Harvey PD, Raykov T, Twamley EW et al (2013a) The factor structure of neurocognition and functional capacity in schizophrenia: a multidimensional examination of temporal stability. J Int Neuropsychol Soc 2013(19):656–663 Harvey PD, Siu C, Hsu J et al (2013b) Effect of lurasidone on neurocognitive performance in patients with schizophrenia: a short-term placebo- and active-controlled study followed by a 6-month double-blind extension.
2012), but when tasks require an association of object with contextual or spatial information, then integration of the hippocampus with the perirhinal cortex occurs (Winters et al. 2010b). Recognition memory tasks in rodents are widely used within many laboratories and are referred to as the object recognition test (ORT) or novel object recognition (NOR) or novel object discrimination (NOD). The “one-trial learning” test which is predominantly used was originally described by Ennaceur and Delacour (Ennaceur and Delacour 1988).