Download Breast Cancer: Textbook for General Practitioners by Professor Dr. Umberto Veronesi (auth.), Professor Dr. PDF

By Professor Dr. Umberto Veronesi (auth.), Professor Dr. Umberto Veronesi (eds.)

The "Europe opposed to melanoma" programme has, from its inception, emphasized the main position which common practitioners needs to play within the activities essential to in attaining its objective of reduc­ ing the prevalence and the mortality from melanoma within the eu neighborhood. basic practitioners, due to their day by day direct and carrying on with touch with sufferers, playa function not just in fundamental prevention and schooling of sufferers, but in addition in motivating their sufferers to just accept secondary prevention and screening, a few of it conducted by way of common practitioners themselves. those preventive actions are as well as their conventional function within the care and administration of sufferers with melanoma at domestic, and increas­ ingly, their function in energetic therapy. In view of the significance of the overall practitioner within the "Europe opposed to melanoma" seasoned­ gramme, the ecu fee, so one can delivering normal practitioners with up to date worthy info, has backed the construction of this sequence of guides on organ dependent cancers, particularly written for common practitioners. MICHEL RICHONNIER Coordinator of the" Europe opposed to melanoma" programme, fee ofthe eu groups, Brussels Preface the current textbook is the second one within the sequence released via the fee of the Euro­ pean groups in the context of the "Europe opposed to melanoma" Programme. After lung melanoma, it was once felt that precedence may be given to breast melanoma, the main widespread neoplastic affliction between eu women.

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Additional info for Breast Cancer: Textbook for General Practitioners

Sample text

Skin alteration is probably the most specific sign of cancer. It usually involves the skin overlying a palpable mass but may be occasionally an isolated sign. Infiltration and ulceration are highly specific and predictive of cancer. Oedema and dimpling are less specific, being possibly due to acute or chronic inflammatory disease, respectively. Enlarged axillary nodes are infrequently reported by the patient although they may be detected on physical examination. The presence of palpable axillary nodes is a very nonspecific symptom being often present, even bilaterally, in most women undergoing physical examination.

All the studies thus far reporting mortality data confirm that screening has a significant impact on breast cancer mortality. Unfortunately, these studies are not homogeneous in design and involve relatively small populations. Thus, further analysis of mortality results and of the optimal screening features is quite complicated. Breast cancer mortality is reduced by screening but the extent of this reduction seems to be age dependent. A significant reduction of mortality in women aged over 49 years has been reported in all studies whereas in women aged 40-49 the impact on breast cancer mortality was absent or not statistically significant.

The situation regarding trends in breast cancer among younger women is obviously not consistent throughout the world and the data from all SEER registry areas {Cancer Registration regions of the United States} do not show any increase in breast cancer incidence in women under the age of 45. 25 In summary, there are many hints emerging from several populations that the rate of increase in breast cancer risk in younger cohorts of women is slowing down, or even falling. It is a situation which requires verification in other population groups not yet investigated and one which merits continual surveillance.

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